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Figure 1


Fig. 1. Characterization of a new LAMP molecule. (A) BAD-LAMP protein sequence showing predicted glycosylation sites (bold and blue), putative di-sulfide bridges between two pairs of cysteins (red line), transmembrane domain (aa 236-256 in blue and underlined) and tyrosine endocytic sorting motif (YKHM, aa 276 in red). (B) Phylogram representation of all the LAMP family members in human and mouse. (C) Tissue distribution of BAD-LAMP by Northern blot. Among all mouse tissues tested BAD-LAMP appears to be expressed specifically in brain as a 2 kb mRNA transcript. Actin mRNA levels are shown as control.





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