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Figure 5


Fig. 5. Mislocalization of HURP, but not TPX2 or TOGp, in RANBP1-depleted mitoses. (A) Unaltered localization of TOGp in RANBP1-depleted mitotic cells. (B) Unaltered localization of TPX2 in RANBP1-depleted mitotic cells. (C) Deconvolution images showing the abnormal organization of HURP (red) over MTs (green) in RANBP1-interfered [RANBP1(i)] mitoses (c,d,g,h), compared with the plus-end-restricted distribution seen in control cells (a,b,e,f). Bars, 10 µm.





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