spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 2


Fig. 2. Panx1 and Panx3 are localized to the cell surface when expressed in NRK cells. Confocal microscopic images of NRK cells expressing untagged Panx1 or Panx3 (A) or GFP-tagged Panx1 or Panx3 (B). Immunolabeling with mouse (anti-Panx1) and human (anti-hPANX1) antibodies revealed that Panx1 and Panx1-GFP were found at the cell surface with increased intensity at cell-cell interfaces when both cells expressed Panx1 or Panx1-GFP. Similar to that observed for Panx1, Panx3 displayed cell surface localization. However, Panx3-GFP was retained within the cell and colocalized with protein disulfide isomerase, an endoplasmic reticulum protein. Bars, 10 µm.





Right arrow Return to article