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Fig. 3. Statistical analysis of Ca2+ sparks in WT and RyR1–/– urinary bladder myocytes. Given is the percentage of cells that produce spontaneous Ca2+ sparks or Ca2+ sparks activated by 10 mM caffeine or membrane depolarization (depolarizing pulses of 50 mV, 100 mseconds from holding potential –40mV) in WT and RyR1–/– myocytes. The number of cells that produce sparks versus the total number of cells tested in each condition is indicated in parentheses.