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Figure 6


Fig. 6. Changes in FKBP12 and FKBP12.6 expression in embryonic RyR1–/– mouse urinary bladder. (A) Semi-quantitative RT-PCR analysis of FKBP12 and FKBP12.6 mRNA in control and RyR1–/– mouse myocytes. (B) Bar graph showing a significant diminution of FKBP12:GAPDH ratio in RyR1–/– mouse myocytes in six different RNA extractions tested in triplicate. (C) Western blot analysis of FKBP12, FKBP12.6 and {alpha}-actin expression in WT and RyR1–/– mouse myocytes. (D) Bar graph of FKBP12 and FKBP12.6 fluorescence area per µg of protein obtained from four mice of each strain. *P<0.05.





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