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Figure 5


Fig. 5. Kar3 bound to tubulin. Binding orientation of Kar3 motor domain on {alpha}β-tubulin, based on docking crystal structures into the EM maps (see Fig. 4). Different parts of Kar3 are coloured as in Fig. 2, including the switch II region in yellow. Loop L8 and helix {alpha}6 are also part of the interface with tubulin. Similar interactions for kinesin and Kif1a are apparent in Fig. 3A,C.





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