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Figure 1


Fig. 1. Domain structures of Hip1r orthologs in different species. Like other Sla2/Hip1 family members, Dictyostelium Hip1r contains an ANTH domain, a central coiled-coil region and THATCH domain as well as proline- and glutamine-rich regions. Over its entire length, Hip1r shares 24% identity with Sla2p, and 20% and 19% identity with mouse and human HIP1R, respectively. Overlap of shaded regions indicates areas of overlap between domains. Dicty, Dictyostelium discoideum; Yeast, Saccharomyces cerevisiae; Mouse, Mus musculus; Pro, proline; Gln, glutamine.





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