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Figure 7


Fig. 7. Isolation of the dystrophin-dystroglycan complex of the K19–/– mouse. The dystrophin-dystroglycan complex was partially purified on a wheat germ lectin affinity column, eluted, and analyzed by SDS-PAGE and immunoblotting, as described in Materials and Methods. K19, K8 and {gamma}-actin eluted with dystrophin (Dys) and β-dystroglycan (Bdg) from control tissue, but only {gamma}-actin eluted with these proteins from K19–/– tissue.





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