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Figure 1


Fig. 1. TGFbeta1 modulation of FAK phosphorylation. (A) Whole lysates of TGFbeta1-treated cells were analyzed for FAK expression (top panel) and specific phosphorylation on tyrosine residues 397 or 925 (bottom panels) by immunoblotting. (B) Mesangial cells serum-deprived for 24 hours were treated with TGFbeta1 (right panels) or vehicle (left panels) for 30 minutes, then fixed and stained for phospho-Y397 FAK (pY397, top) or phospho-Y925 FAK (pY925, bottom). Bar, 20 µm.





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