Supplemental Figure S1
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Fig. S1. Smad2 activation is not altered in ALK5 mutant embryos. Transverse sections of E9.5 wild-type (A-D9) and ALK5−/− (E-H9) embryos stained with PSmad2 antibody showing positive cells in the neural crest and the mesenchyme tissue in the brain (A,A9,E,E9), neural tube, and branchial arch (B,B9,F,F9), heart (C,C9,G,G9) and somites, dorsal aorta and umbilical vein (D,D9,H,H9). Scale bar, 0.5 mm. bba, branchial arch artery; cv, cardinal vein; da, dorsal aorta; fg, foregut, ht, heart; hv, head vein; nt, neural tube; ov; otic vesicle phv, primary head vein; s, somite; uv, umbilical vein; va, vitelline artery.
