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Figure 1


Fig. 1. Schematic representation of wild-type proteins, mutants and constructs. The transmembrane and extracellular domains of NPP3 and NPP1 are drawn in black and white, respectively. The amino acid sequences of the cytoplasmic tails are given in single letter code. Amino acids altered by site-directed mutagenesis are underlined. In the NPP3-AAASLLAP construct, the sequence AAASLLAP of NPP1 was inserted after the second amino acid at the N terminus of NPP3. Constructs are not drawn to scale.





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