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Figure 6


Fig. 6. Alternate forms of veil protrusion. The upper panel of each subsection contains a low magnification image of the growth cone, with the region of interest boxed, a single phase-contrast overlay, and a low magnification EM of the region of interest. (A) Nascent veil protrusion (6.8 µm/minute) along a single filopodium. Veil contains a dense network of filaments connected to filopodial shaft. (B) Veil formation (8.3 µm/minuts) isolated from lamellipodium. Dense network interconnects two filopodia shafts. (C) Established Filopodia `independent' protrusion (8.1 µm/minute). Veil organization is a mixture of dense network and loosely bundled long filaments. Boxed regions (a-c) show branched filaments in the network, pseudo-colored cyan for visualization. (D) Nascent filopodia-`independent' protrusion (1.1 µm/minute). Veil displays multiple finger-like protrusions containing dense network and some long filaments.





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