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Figure 8


Fig. 8. Correlation of Arp3 location with veil dynamics. The upper panel of each subsection contains a low magnification image of the growth cone, with the region of interest boxed, a single phase-contrast overlay, and a low magnification EM immunostained against Arp3 in the region of interest. (A) Protruding filopodia (5.2 µm/minute)-associated veil with a concave leading edge. (B) Retracting filopodia (1.7 µm/minute)-associated veil with sparse actin network. (C) De novo veil initiation from filopodial shaft (*), which travels (11.3 µm/minute) toward the growth cone. (D) Representative example of a veil arising de novo from a phase-dense spot along the shaft of a filopodium.





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