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Figure 7


Fig. 7. Nod2 localization in ribbon-like membrane ruffles induced by RacQL. (A,B) COS-7 cells were transfected with 1 µg of plasmid expressing the HA-tagged wt Nod2 protein and 2 µg of plasmid encoding the constitutively activated Rac1 mutant (Rac QL). Twenty-four hours post transfection, cells were stained for Rac1 and F-actin (A) or for Rac1 and Nod2 (B). Images were obtained by confocal microscopy (Leica TCS NT). Arrows indicate areas of colocalization.





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