spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 9


Fig. 9. Involvement of SMAD signaling in cumulus expansion. (A) Effect of medium only, SB431542 (10 µM) or SIS3 (20 µM) on cumulus expansion in COCs treated with EGF (10 ng/ml) for 15 hours. White arrows indicate cumulus cells attached to the culture dish in COC treated with SIS3. (B) Expansion of COCs treated with EGF (10 ng/ml) alone or with 1 µM SB431542 or 0.1 µM SB431542 for 15 hours. (C) Effect of SB431542 (10 µM) or SIS3 (20 µM) on expression of cumulus expansion transcripts in COCs treated with EGF (10 ng/ml) for 6, 8 and 10 hours. Transcripts were measured by real-time PCR and normalized to Rpl19 mRNA. abcP<0.05, significant differences.





Right arrow Return to article