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Figure 7


Fig. 7. The UPS reporter system in cortex cultures of UbG76V-GFP transgenic mice. (A) UbG76V-GFP tg organotypic cortex cultures without treatment with proteasome inhibitors. (B) UbG76V-GFP tg cortex cultures treated with 1 µM epoxomicin. The GFP-reporter substrate only accumulated after proteasome inhibition. Bars, 50 µm.





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