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Figure 1


Fig. 1. Biosynthesis of VWF. (A) Block diagram showing the domains of VWF (D1-C), and the regions of the mature protein (D'-CK) involved in dimerisation. Nt, N-terminus; Ct, C-terminus. (B) Working model describing main events occurring during formation of VWF tubules and multimers, with intracellular locations.





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