spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 4


Fig. 4. The sizes of ERES-like clusters in the simulation. The mean size <n> of ERES-like clusters decreases upon accelerating the binding kinetics (e.g. by depleting transport-competent cargo) in the case of biased binding (A) and free binding (B). Here, Kon was increased while keeping Koff=Kon/2, Kon, 2Kon (light grey, dark grey, black fill). Using biased binding – that is, a cooperativity of COPII complexes – the ERES-like clusters were significantly larger (compare B with A). (C) The distribution of normalized sizes, p(a) with a=n/<n> always showed a broad shape with a cut-off that is imposed by the smallest visible cluster.





Right arrow Return to article