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Figure 3


Fig. 3. Mitotic importin β cargo gradients scale with the size of the mitotic spindle. (Left) Mitotic spindles visualized in a live HeLa cell and in X. laevis egg extract using incorporated Rhodamine-labeled tubulin. (Right) Pseudocolor image showing the signal of the Rango FRET sensor, which reports on the RanGTP-induced release of importin {alpha} and importin β cargos. The images are displayed at the same scale (scale bar, 10 µm). Adapted from Kalab et al. (Kalab et al., 2006) with permission.





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