spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 3


Fig. 3. Muscle pathology in Lama2 mutants. (A-D') Low (A-D) and high (A'-D')-magnification images of age-matched (P59) plantaris muscles stained with H&E. (A) Normal muscle fibers were closely aligned, had a narrow distribution of calibers and contained peripheral nuclei. (B) In nmf417-homozygote muscles, the myofiber population contained many smaller fibers, which were interposed by endomysial connective tissue and monocyte-rich lesions, and many fibers contained central nuclei. (C) Dystrophic changes in dy2J muscle were comparable to those in nmf417 muscle. (D) Dystrophic changes in dy-homozygote muscle were more severe than in nmf417, including increased fiber loss and fibrotic lesions. Scale bar: 300 µm (A-D); 75 µm (A'-D').





Right arrow Return to article