spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 7


Fig. 7. Dnm1p and Vps1p have distinct functions. Dnm1p overexpression does not restore the vacuolar fusion defect in vps1{Delta} cells, and Vps1p overexpression does not rescue the mitochondrial fission defect in dnm1{Delta} cells. (A) Vacuoles were visualised by allowing cells to take up FM4-64 to steady-state levels. The vacuolar membrane is clearly visible in wild-type (WT) cells and in vps1{Delta} cells expressing Vps1p, whereas unfused, fragmented vacuoles are visible in vps1{Delta} cells and in vps1{Delta} cells overexpressing Dnm1p. (B) Cells expressing mito-GFP were grown to log phase on 2% glucose. dnm1{Delta} cells overexpressing Vps1p show the mitochondrial fusion defect typical of dnm1{Delta} cells. Scale bar: 5 µm.





Right arrow Return to article