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Fig. 9. SuUR and Su(var)2-5 genes are expressed independently. RT-PCR analysis of SuUR, Su(var)2-5 and rp49 (control) expression levels in salivary glands of wild-type OregonR, SuUR, Su(var)2-503/Su(var)2-505 heterozygotes (HP1 null mutants), hs-SuUR (SUUR overexpression) and hs-HP1 (HP1 overexpression) strains. Minus and plus signs indicate the absence and presence of reverse transcriptase in RT-PCR reaction, respectively. Transcription of Su(var)2-5 gene in Su(var)2-503/Su(var)2-505 heterozygotes is not abolished because the Su(var)2-505 mutation is caused by a dinucleotide deletion in the coding region (Eissenberg et al., 1992); the molecular lesion associated with the Su(var)2-503 mutation is unknown.