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Figure 2


Fig. 2. Membrane recruitment of dephospho-β-catenin is an early event in the Wnt response. Kep1 cells were induced with Wnt3A for 30-240 minutes and nuclear and (dephospho-)β-catenin plasma membrane accumulation was recorded in 100-130 cells (see Materials and Methods for details on image acquisition and analysis). (A) Representative fields of cells. (B) Box plots representing quantification of plasma membrane and nuclear accumulation. Medians are indicated in red. P values indicated are the results of Mann-Whitney tests.





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