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Figure 7


Fig. 7. Dephospho-β-catenin is enriched on the plasma membrane in human intestinal crypts. (A) Low-power photomicrograph of a normal human small intestinal crypt-villus axis. Dephospho-β-catenin is enriched on the crypt epithelial plasma membrane when compared with the plasma membrane labeling on differentiated villus cells. (B) High-power photomicrograph of crypt compartment shown in A. Crypt epithelial cells including the presumptive intestinal epithelial stem cells or crypt base columnar (CBC) cells (Barker et al., 2007) show robust plasma membrane labelling (arrows).





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