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Figure 5


Fig. 5. Site morphology. Merges were prepared as in Fig. 3D (A-D,F) and Fig. 4C (E). Arrows indicate transcription sites marked by gold particles. (A) Site marked by two gold particles surrounded by space free of P and N. (B) Site marked by particles surrounded by chromatin (arrowhead marks RNPs and/or nucleosomes). (C) Three sites marked by particles lying close to each other. (D) Site marked by particles lying near other gold-free structures (arrowheads) that have dimensions and P:N ratios typical of sites. (E) Site containing many P-rich granules (arrowhead) smaller than nucleosomes. This site was selected by correlative microscopy because there are no obscuring gold particles (but similar granules are seen by immunogold labelling). Inset, P map. (F) Site lying near IGC (arrowhead). Scale bars: 100 nm (A,B,D,E); 50 nm (C,F).





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