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Figure 6


Fig. 6. Cartoon illustrating a section through a site. An active polymerase (attached to a core) reels in its template (blue arrow) as it extrudes its transcript; only one of ~eight polymerising complexes on the surface is shown. The upper face of the section illustrates how this structure appears in an ESI merge. The N-rich core appears green, except for several (yellow) granules that each contain ~70 P atoms; nucleosomes and RNPs (both yellow) are found on/near the surface. Sectioning often removes one or other pole with any associated templates/transcripts, while leaving those tethered to equators. When viewed from above, most RNA is then seen associated with equators, with little apparently lying within cores (see Materials and Methods for quantitative analysis).





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