spacer gif spacer gif spacer gif spacer gif spacer gif
 QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    


Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.


Figure 9


Fig. 9. EGF attenuates TGFβ1-mediated migration of oral keratinocytes, but increases TGFβ1-mediated migration of OSCC cells. Serum-starved OKF6 and UMSCC1 cells were untreated, treated with EGF (20 ng/ml) or TGFβ1 (10 ng/ml), or pre-treated with EGF (20 ng/ml) for 30 minutes and then treated with TGFβ1 for 24 hours. The cells were then added to transwell chambers that had been coated with type I collagen, for additional 24 hours in the presence or absence of TGFβ1 and/or EGF. Nonmigratory cells were removed from upper chamber, and migrating cells were counted. *P<0.05, significantly different from the EGF(–),TGF-b1(+) OKF6 cells. The results are representative of at least two independent experiments.





Right arrow Return to article