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Figure 2


Fig. 2. The tetraspanin protein CD9 alters the stability of the processed forms of transmembrane TGF{alpha}. CHO cells expressing TGF{alpha} or coexpressing CD9 and TGF{alpha} were 35S-Met–35S-Cys pulse-labeled for 12 minutes, chased for times indicated, lysed and subjected to immunoprecipitation with anti-TGF{alpha} antibodies. (A) SDS-PAGE analyses of immunoprecipitated 35S-labeled TGF{alpha}. (B) Quantification of the transmembrane TGF{alpha} bands as a function of the chase time.





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