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Figure 1


Fig. 1. Shape and surface topography of the HSV-1 capsids studied by EM and AFM. (A) EM image of the capsid preparation. (B) HSV-1 capsids adsorbed to the surface of poly-L-lysine-coated mica (1.60x1.38 µm). (C,D) A single capsid with the typical hexagonal outline (C) and its cross section (D). (E) Two capsids with apparent icosahedral symmetry and clearly distinguishable triangular faces (510x560 nm). (F) A fragment of the HSV-1 surface with clearly distinguishable capsomeres (100x100 nm). (G,H) A penton surrounded by five nearest neighboring hexons (G) and a hexon (H). Pentons and hexons images are 40x40 nm.





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