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Fig. 2. Structural integrity of HSV-1 capsids on various surfaces. AFM images (A,C,E) and cross-sectional graphs (B,D,F). HOPG (A,B) and poly-L-lysine-coated mica (C,D) are capable of adsorbing intact capsids. (E,F) On the surface of poly-L-lysine-coated glass, capsids undergo complete disassembly which yields
40-nm-high spherical structures. Coiled genomic material also adsorbs to the surface. The AFM images are 3.5x3.5 µm.