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Figure 6


Fig. 6. TRPC6-induced dendritic growth depends on CREB activity. (A) The total lysates of the cells transfected with the indicated plasmids were blotted with antibodies to phosphorylated CREB or total CREB. (B) Quantification of CREB phosphorylation in the neurons transfected with the indicated constructs. *P<0.05 or **P<0.01 versus control. (C) Representative images of the neurons transfected at 3 DIV for 4 days with wild-type TRPC6 (WTC6) and the dominant-negative CREB mutant (KCREB). Scale bar: 20 µm. (D,E) Quantification of total dendritic tips (D) and total dendritic length (E) of the neurons shown in C. **P<0.01 versus ctrl. All data are the means ± s.e.m. n.s., not significant.





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