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Figure 2


Fig. 2. Functional assays for Nok deletions. (A-G) Phenotypes of (A) wt, (D) nokm520 mutant, or (B,C,E-G) nokm520 mutants that were injected with mRNA encoding different deletions of Nok. Insets are details of the corresponding RPE phenotype. Note that the cobblestone-like appearance of this tissue is severely disrupted in nokm520 (D), nok{Delta}Crb (F) and nok{Delta}C (G) mutants but rescued in the other mutants and WT. (H) Summary of rescue efficiencies of the different deletion constructs in the nokm520 mutant background for two aspects of the phenotype. RPE, retinal pigment epithelium.





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