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Fig. 3. Status of the AR-Skp2 pathway in various prostate-cancer cells as indicated. (A,C,D) Western blots and relative cell proliferation of LAPC4, C4-2 and 22Rv1 cells, respectively, after transduction with the indicated lentiviral constructs and culturing in 10% FBS medium. These experiments were performed twice with similar results. (B) Western blots of CWR22 xenograft tumors harvested at the indicated times.