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Figure 8


Fig. 8. Roles of putative cell-death mediators in lipotoxic cell death of S. pombe. (A,B) Viability of the indicated TKO cells in rich medium. (C,D) Viability of the indicated TKO cells in minimal medium. {Delta}pca1, {Delta}rad9, {Delta}pck1 and {Delta}bzz1 TKO cells exhibited attenuated cell death as compared with DKO cells only in minimal medium. Deletion of pck2+ or apg6+, however, had no effect in both media. Values shown are means with s.e.m. from independent experiments (n>=3). +/*P<0.05; ++/**P<0.005; +++/***P<0.0005.





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