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Figure 8


Fig. 8. PKC plays only a minor role in CCR7 endocytosis. 300-19 CCR7 cells were pretreated or not with 10 µM PKC inhibitor Bim for 30 minutes and stimulated with either 1 µM PMA or 2 µg/ml CCL19 for 30 minutes at 37°C as indicated. Surface expression of CCR7 was then determined by flow cytometry. Relative mean median fluorescence ± s.e.m. of four experiments is shown.





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