spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 7


Fig. 7. TRPV4 contributes to GTTR retention in KPT2-TRPV4 cells in an endolymph-like extracellular environment. After 1 minute of GTTR treatment in PBS containing Ca2+ at 1.25 mM, KPT2-pBabe and KPT2-TRPV4 cells had similar levels of GTTR (A,D). After incubation in clearance buffer, KPT2-pBabe cells had lower GTTR fluorescence levels compared with KPT2-TRPV4 cells (B,C,E,F). Treatment with 10 µM RR to block inward currents accelerated GTTR clearance from KPT2-TRPV4 cells (G,H). Fluorescence intensity of cytoplasmic GTTR was quantified and statistically analyzed, and data are shown as mean ± s.d. (I). **P<0.01. Scale bar, 20 µm.





Right arrow Return to article