spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 3


Fig. 3. BAPTA-am loading reversed the disassembly of STIM1 clusters by histamine. (A) Representative images of the sensitivity of pre-existing subplasmalemmal STIM1 clusters to histamine and their recovery upon reduction of [Ca2+]cyto (n=6). (B) BAPTA reversed the decomposition of pre-existing subplasmalemmal STIM1 clusters upon histamine stimulation independently from extracellular Ca2+ (n=6). (C,D) Cytosolic Ca2+ signaling (C) and kinetics of subplasmalemmal STIM1 clustering (D) in response to 100 µM histamine in the presence of 2 mM extracellular Ca2+ in YFP-STIM1-expressing cells that were loaded with either fura-2-am (n=6) or with fura-2-am and BAPTA-am (n=6). *P<0.05 versus the respective compared data set.





Right arrow Return to article