spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 1


Fig. 1. Subcellular localization of the ErbB family members. (A) CHO cells expressing EGFR-CFP, ErbB2-YFP, ErbB3-CFP or ErbB4-JMa-GFP were serum-starved for 24 hours at 37°C, and then observed by confocal microscopy. Note that the FP-fused EGFR, ErbB2 and ErbB4-JMa were localized in the plasma membrane, whereas ErbB3-CFP was mainly in the nucleus. (B) CHO cells co-expressing EGFR-YFP and ErbB3-CFP, ErbB2-YFP and ErbB3-CFP, or ErbB4-JMa-YFP and ErbB3-CFP were serum-starved, and then observed by confocal microscopy. Note that a large fraction of ErbB3-CFP was localized in the plasma membrane when co-expressed with EGFR-YFP or ErbB2-YFP. By contrast, the majority of the ErbB4-JMa-YFP protein was localized in the nucleus when co-expressed with ErbB3-CFP. Bars, 10 µm.





Right arrow Return to article