spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 6


Fig. 6. (A) Intensity of OHC immunolabeling with anti-βV spectrin (squares) and anti-prestin (circles) antibodies plotted against age (days after birth). The values obtained for the apical turns (80-100%, see Fig. 5B) were averaged, and then normalized to the corresponding average value obtained in P20 mice. (B-D) Parallel distribution of βV spectrin and prestin within differentiating OHCs. (B) At P3, the bulk of βV spectrin staining is diffuse within the cytoplasm. At this stage, {alpha}II spectrin can be detected in the cuticular plate and along the cell lateral wall. In some OHCs from the base of the cochlea, prestin can be detected, essentially at the apico-lateral cell membrane. (C) At P5, βV spectrin and prestin are both detected in the forming cortical lattice. (D) From P8 onwards, the labeling extends along the entire length of the OHC lateral wall. Scale bars: 5 µm.





Right arrow Return to article