spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 7


Fig. 7. Effect of overexpression of splicing factors on VEGF isoform production. (A) Retinal pigmented epithelial cells were transfected with splicing factors and distal splicing isoforms (VEGFxxxb) and total VEGF levels determined by SDS-PAGE and western blotting. (B) Densitometry of cell lysates showing expression of VEGF165b and total VEGF after transfection with splice factors. (C) The difference in VEGF expression between VEGFxxxb and total VEGF is shown relative to controls for splice factors. Solid line indicates an equal balance between the two sets of isoforms. Values below the line indicate anti-angiogenic balance, above a pro-angiogenic balance (*P<0.05 compared with untreated, ANOVA, Dunnett's test. n=3).





Right arrow Return to article