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Fig. 1. Inhibition of traction forces in Capn4–/– fibroblasts. (A,B) Vector plots of traction stress indicate magnitude and direction of traction stresses exerted by cells on the substrate, for Capn4–/– cells stably re-expressing the small subunit (A) and Capn4–/– cells (B). (C) Bar graph shows average integrated traction forces magnitude from each type of the cells. Capn4–/– cells show a significant reduction in traction forces compared with wild-type or rescued cells (Student's t-test P=0.0003).