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Figure 5


Fig. 5. Inhibition of ERK1/2 activation promotes macrophage spreading. WT BMMs were plated on glass coverslips in the presence or absence of 1 µg/ml U0126. (A) Representative images of cells stained for F-actin. (B) Cell spread area was quantified at the indicated time points. The mean spread area ± s.e.m. from three separate experiments is shown. ***P<0.001 comparing WT+U0126 to untreated WT; n=~50 cells per time point per experiment. Scale bars: 5 µm.





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