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Figure 1


Fig. 1. Vimentin expression constructs and eye phenotype. (A) Schematic representation of the constructs used for expression of wildtype, R113C point-mutant (VimR113C) and C-terminal truncated (Vim{Delta}C2B) vimentin transgene. All constructs are based on the mouse vimentin gene with its own regulatory elements. (B) Note turbid lens in a 22-week-old animal expressing the VimR113C mutant (arrow).





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