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Figure 5


Fig. 5. Numerical CIN in various cancers. (A) Non-diploid tumors display CIN much more often than diploid tumors. The percentage of diploid (blue) and non-diploid (red) tumors with cell-to-cell variability in chromosome number has been plotted. Bracketed numbers indicate the number of tumors analyzed for diploid and non-diploid tumors, respectively. (B) Numerical CIN is less frequent in diploid and tetraploid tumors than in aneuploid tumors. The percentage of tumors with CIN is plotted against the average chromosome number. Every data point represents at least five tumors. The trend line represents the moving average in the second period (i.e. each point of the trend line represents the average of the two neighboring data points). The Mitelman Database of Chromosome Aberrations in Cancers was used as a source of the analyzed data (http://cgap.nci.nih.gov/Chromosomes/Mitelman).





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