spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 4


Fig. 4. unc-94/tmd-1(RNAi) strongly enhances actin disorganization in an unc-78-null background. (A) Localization of TMD-1 and UNC-78 in unc-78 mutant and unc-94/tmd-1(RNAi) muscles, respectively. TMD-1 (a,d) and actin (b,e) were immunolocalized in the body-wall muscle of wild-type (a-c) and unc-78(gk27) (d-f). Merged images are shown in c and f (TMD-1, green; actin, red). UNC-78 (g,j) and actin (h,k) were immunolocalized in the body-wall muscle of wild-type (g-i) and unc-94/tmd-1(RNAi) (j-l). Merged images are shown in i and l (UNC-78 in green and actin in red). (B) Effects of unc-94/tmd-1(RNAi) on worm motility in an unc-78 null background. Wild-type and unc-78(gk27) were examined. Data are the mean ± s.d., n=10. Asterisks indicate P<0.005 by t-test comparing control RNAi experiments and unc-94/tmd-1(RNAi) for each strain. (C) Appearance of wild-type (a,c) and unc-78(gk27) (b,d) worms treated with control dsRNA (a,b) or unc-94/tmd-1(RNAi) (c,d) on agar plates. (D) Actin filament organization in the body-wall muscle of wild-type (a,b) and unc-78 (c,d) treated with control dsRNA (a,c) or unc-94/tmd-1(RNAi) (b,d).





Right arrow Return to article