spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 1


Fig. 1. RUNX1/AML1 and AML1-ETO are targeted to distinct subnuclear locations. Immunofluorescence microscopy for endogenous RUNX1/AML1 (red) and AML1-ETO (green) with DAPI staining (blue) in Kasumi-1 cells as well as merged images are shown. RUNX1/AML1 and AML1-ETO fusion protein are predominantly present in the nucleus but do not colocalize in the Kasumi-1 cells. An antibody detecting ETO was used to visualize the AML1-ETO fusion protein, whereas an antibody recognizing the C-terminal domain of RUNX1/AML1 was used to detect endogenous RUNX1/AML1.





Right arrow Return to article