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Figure 4


Fig. 4. Depletion of AP-2 subunits perturbs endocytic trafficking of Arf6-pathway cargoes. Live cells depleted of {alpha}-adaptin (left) or µ2-subunit (middle) were incubated with antibody against β1 integrin. Samples were fixed and stained with {alpha}-adaptin antibody (top) to identify depleted cells. Right, live {alpha}-adaptin-depleted cells were incubated with antibody against MHCI. Cells were fixed and stained with {alpha}-adaptin antibody. Arrows indicate depleted cells.





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