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Fig. 6. Nucleostemin protects against drug-induced death and cell-cycle arrest. Cell-cycle analyses show that nucleostemin overexpression (NSOE, black bars) has a significant effect in protecting against ActD and MPA-induced cell death (sub-G1) and reducing the S-phase block triggered by ActD. Bars, mean of three independent duplicate experiments (n=6); error bars, s.e.m.; *P<0.01; **P<0.001.