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Figure 1


Fig. 1. Phylogenetic analysis of the SFRP family obtained by comparison of the CRD amino-acid sequences. Members displaying the most similarities in amino acid sequences cluster together and the branch length is proportional to divergence (percentage of nucleotide changes). Numbers indicate the bootstrap confidence for each node (n=1000). Different subfamilies are coloured differently. am, Ambystoma mexicanum (axolotl); c, Gallus gallus (chick); Ce, Caenorhabditis elegans (nematode); ci, Ciona intestinalis (sea squirt); Cr, Crescent; h, Homo sapiens (human); m, Mus musculus (mouse); ol, Oryzias latipes (medaka fish); S, Sfrp; sp, Strongylocentrotus purpuratus (sea urchin); Sz, Sizzled; X, Xenopus laevis (African clawed frog); z, Danio rerio (zebrafish).





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