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Figure 3


Fig. 3. RNAi depletion of IKAP results in migration defects in rat cerebellar granule neurons that can be rescued by full-length but not FD-IKAP. (A) Migration of cerebellar granule neurons transiently transfected with designated IKBKAP (M2) or scr siRNA oligonucleotide and/or IKBKAP plasmids was quantified and normalized to control levels (means ± s.d.; n=4; **P<0.01; ***P<0.001). (B) Viability of neurons expressing designated IKBKAP or scr siRNA and/or IKBKAP plasmids (means ± s.d.; n=4).





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